Skeletal Characteristics of Children and Adolescents with Turner Syndrome

Turner syndrome (TS) is a chromosomal disorder characterized by short stature and gonadal dysgenesis, the latter of which requires estrogen replacement therapy (ERT) to induce maintain secondary sexual characteristics. Insufficient ERT associated with compromised skeletal health, including bone fragility, in adults TS. In particular, insufficiency during adolescence critical because acquisition defective mass this period results impaired strength later life. addition mass, geometry also crucial factor influencing strength; therefore, more detailed understanding characteristics both childhood their relationships status needed prevent health adulthood Although delay initiation lower mineral density adulthood, limited information currently available on effects geometry. Herein, we summarize current knowledge children adolescents TS sufficiency, discuss potential limitations protocol for order achieve better adulthood.